First of all, tourism is an activity that makes our city very well, definitely.
Santiago has many places, estates and architectural creations to see. In my opinion every corner of our City may be interesting to see and hear your story for tourists.
Forgetting places that obviously would be in a list of a tourist such as La Moneda, Plaza de Armas, Plaza de la Constitution,etc. I want to talk about the neighborhoods, because the essence of Santiago is in their neighborhoods, each with identity, architecture and history itself.
Santiago Centro neighborhoods like the pulse of the city in its full expression, where only you can feel it walking around, or Bellavista where we have a open air museum, and Alonso de Cordova is one of the most elegant avenues of the City, or Matucana wich combines streets of residential areas with commercial activity, or Brasil with its colonial buildings, or Lastarria with a mixture of architectural styles. These are places that have to see if you come to visit our city, we must not think of the biggest names or the most widely known buildings, think with an open mind, without prejudices and explore Santiago and activities like the sports, gastronomy, folklore, literature, music, etc to make you feel Santiago, Chile as a Chilean experience.
Finally I think the tourist bus is different than the tourist walking and goes into our culture, I am sure that tourists who walked and made his own tour will return home with more stories, and interesting things to tell and remember.